Ethical Clinical Trial Of Lesser Known Homeopathic Remedies In Infertility In Females

Abstract-

Background & Objective:  Homoeopathy with time honoured results, has a great number of cured cases of infertility, but without much evidence. So, it is imperative to show scientifically the scope of homoeopathy in treating infertility cases.

Materials and Methodology: 7 lesser known medicines (Alteris farinosa, Janosia Ashoka, Viburnum opulus, Euphonium, Ustilago, Bacillus sycocuss, Bacillus morgan) were prescribed to the sample size (n=23), at the project site O.P.D/I.P.D. of Homoeopathy university, Saipura, Jaipur and Dr Madan Pratap Khunteta Homoeopathic Medical College, Hospital & Research Centre, Station Road, Jaipur & its extension O.P.D.’s. for study within 12 months.

Result-In the present study 7 (30.43%) patients were prescribed Janosia Ashoka amongst whom 2(28.57%) showed marked improvement, while 5(71.43%) remained in the state of status quo.

Conclusion- Study has shown encouraging and effective treatment in infertility in females.

Keywords- Janosia Ashoka, Homoeopathy, Infertility, Aletris farinosa, Viburnum opulus, Euphonium, Ustilago, Bacillus morgan, Bacillus sycocuss

Introduction-

Infertility is defined as 1 year of unprotected intercourse without pregnancy.

This condition may be further classified as primary infertility, in which no previous pregnancies have occurred, and secondary infertility, in which a prior pregnancy, although not necessarily a live birth, has occurred. About 12% of the total couple population or more than 7 Million couples accounts for the number of couples having difficulties in getting pregnant.

Motherhood is the greatest boon bestowed upon a woman by God. Having children strengthens the family bonding.

Infertility represents life crisis. The couple often reflects this as their lives become on hold, infertility involves loss of an image of bearing and raising child, of experiencing pregnancy. Sterility in some communities is regarded as a disgrace, as a mark of divine displeasure, and as grounds for divorce, depression and even for compulsory suicide.

Almost 10 to 15% of couples are suffering from infertility, the overall incidence is increasing in spite of advancement in diagnostic as well as therapeutic procedures and infertility procedures have doubled in amount, in a decade.

Multiple etiological factors are considerable for infertility. Generally, they can be divided into obstructive and non–obstructive causes¹. Among non-obstructive causes of infertility, other systems of medicine don’t have much scope.

As we are provided with a large number of remedies and their exhaustive materia medica large number amongst them are well proved but we should also try to explore those whose fields are not explored to that extent. Only with this approach, we will be able to justify our long list of medicines and good statistics obtained, will prove to become pillars of our field.  Moreover, the study with selected remedies is always more focused and gives more scientific results; it also provides the opportunity to explore fields of medicines which are not explored to that extent.

Objectives of the study-

• To study the efficacy of homoeopathic medicines in the treatment of infertility in females.
• To enhance the knowledge of materia medica in cases of infertility in females.

Material and Methodology-

The study was conducted at O.P.D./I.P.D.of Homoeopathy University, Saipura, Sanganer and Dr M.P.K. Homoeopathic Medical College &Research Centre, Station Road, Jaipur from 2010 to 2013 for a total period of 3 Years.

A sample size of n=23 and 7 lesser known remedies were selected for the studies. The selected medicines were:

ALETRIS FARINOSA

1. Menses are premature and profuse with labour-like pain.
2. Amenorrhoea or delayed menses from atony accompanied by the weariness of mind and body, abdomen distended, bearing down pain.
3. Menorrhagia with dark coagulated blood.
4. Leucorrhoea due to weakness and anaemia.
5. The habitual tendency to abortion.
6. Prolapse from muscular atony.
7. Sterility from uterine atony³.

USTILAGO MAYDIS

1. Menses – half liquid, half clotted, aggravated from slightest provocation.
2. Menses that had ceased returns again, are of bright red colour, soreness and bearing down in left side preceding the flow and partially ceasing with it.
3. Menorrhagia of climaxes, post-partum and abortion.
4. Yellow and offensive leucorrhoea.
5. Pain, swelling and tenderness of left ovary.
6. Constant pain under left breast between period.
7. Uterus hypertrophied, prolapsed, cervix sensitive, spongy.
8. Suppressed and vicarious menses.

VIBURNUM OPULUS

1. Menses late, scanty, lasting for few hours, offensive in odour with crampy pain extending to thighs.
2. Bearing down pains before menses.
3. The ovarian region feels heavy and congested.
4. Aching in sacrum and pubes with pain in anterior muscles of thighs during menses.
5. Excoriating leucorrhoea.
6. Smarting and itching of genitalia.
7. Sterility due to frequent and very early miscarriage.³

JANOSIA ASHOKA

1.White, yellow, acrid and watery leucorrhoea.

1. Menses irregular, too late or too early.
2. Menstrual blood – black and clotted.
3. Pain in the back and lower abdomen during menses.³

EUPHONIUM

1. Menses – too early and copious.
2. Burning and stitches in chest and heart, irritability and disinclination to talk during menses.
3. Yellow, gushing leucorrhoea with severe backache after menses.
4. Sore pain between labia during urination.
5. Labia swollen and pruritis pudendi.
6. Chronic tubal disease.
7. Uterine flexion².

BACILLUS MORGAN

1. Frequent, painful micturition.
2. Corrosive leucorrhoea, fetid, yellow, brownish or greenish.
3. Menorrhagia and metrorrhagia.³

BACILLUS SYCOCUSS

1. The pain of the left ovary.
2. Leucorrhoea, profuse, yellowish, foetid, corrosive.
3. Troubles of the menstrual cycle, with prolonged delay. Oligomenorrhoea.
4. Irritating urine with a strong smell.
5. Tenesmus of the bladder.³

A case taking proforma was specially designed for the study. The detailed case taking and clinical examination, laboratory diagnosis was carried out to diagnose.

Inclusion criteria

Following case were included irrespective of their caste, religion and duration of illness:

• Females in the reproductive age group were included in the study
• Cases indicating symptoms of selected drugs.
• Diagnosed case of female infertility, taking treatment from other systems of medicine, feeling no relief and seeking Homoeopathic treatment.
• Diagnosed case of female infertility, taking treatment from other systems of medicine, under control, but seeking Homoeopathic treatment.
• Cases seeking Homoeopathic treatment.

Exclusion Criteria

The cases without proper follow up were excluded from the study.

Result-

Out of 23 patients taken for study, 19 (82.61%) patients were of primary infertility, 4 (17.39%) patients were of secondary infertility.

S.No.	Type of Infertility	No. of Patients	Percentage
1.	Primary	19	82.61%
2	Secondary	4	17.39%
	Total	23	100%

Inferences- Based on clinical symptoms and pathological investigations.

It was inferred that out of 23 patients taken for study, 2 (8.69%) patients showed marked improvement, while 21 (91.31%) patients remained in the state of status quo.

S.No.	Result	No. of Patients	Percentage
1.	Marked Improvement	2	8.69%
2	Status Q	21	91.31%
	Total	23	100%

It was observed that out of 7 cases who were prescribed Janosiaashoka, 2(28.57%) showed marked improvement, while 5(71.43%) remained in the state of status quo.

S.No.	Result	No. of Patients	Percentage
1.	Marked improvement	2	28.57%
2	Status Q	5	71.43%
	Total	7	100%

Discussion:

In the present study, 7 medicines were used. It was inferred that out of 23 cases taken for study, 8(34.78%) patients were prescribed Alteris farinosa,7 (30.43%) patients were prescribed Janosiaashoka, 5 (21.74%) patients were prescribed Viburnum opulus,2(8.69%) patients were prescribed Eupionum, and only1(4.35%) patient was prescribed Ustilago. While Bacillus sycocuss and Bacillus morgan could not cover any case.

Conclusion:

The study showed encouraging results and effectiveness of Janosia Ashoka in the treatment of infertility in females. Moreover cases complicated by irreversible pathological changes viz. PCOD, fibroid and polymicrobial infection PID have also shown signs of improvement.

Aletrisfarinosa, Viburnum opulus, Euphonium, Ustilago, Bacillus morgan and Bacillus sycocussrequire an enhanced study on a large number of patients to prove their efficacy.

References:

1. Riley David, cases of infertility and pelvic inflammatory disease,1^st Edition
2. O.A.Julian, MateriaMedica Of Nosodes With Repertory, New Delhi, 1 Edition, B.Jain Publishers, 1 Jan 2003
3. BoerickeW., Pocket Manual of Homeopathic MateriaMedica, 3^rd Edition, B.Jain  Publishers, New Delhi, Reprint Edition 2008, Page No -1044,590,991,1010,1014
4. Clarke J. H., Dictionary of Practical MateriaMedica, New Delhi, B.Jain  Publishers.

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